5-HTP & Vitamine B

5-HTP + Vitamin B Complex – Plant-Sourced Mood & Sleep Support

Plant-sourced 5-HTP from Griffonia simplicifolia with B Vitamins for mood support, stress resilience & healthier sleep

30 capsules • 260 mg per capsule • Designed for adults • Take after food; avoid milk/protein drinks

Product Quick Facts

• 30 capsules — 260 mg total per capsule (5-HTP from Griffonia simplicifolia + Vitamin B3 (niacin) & B5 (pantothenic acid))
• Mechanism: supports serotonin → melatonin pathways for natural mood and sleep regulation
• Not a medicine: not for children, pregnant/nursing women, or people with chronic illness
• Critical safety note: Do not combine with SSRIs/MAOIs — consult a healthcare professional before use

Primary Benefits

Mood & Sleep Support

• Mood & emotional balance support through serotonin pathway enhancement
• Sleep onset & quality improvement via melatonin precursor pathway activation
• Stress resilience and evening relaxation for better wind-down routines
• Appetite regulation assistance for some users seeking natural balance

Ideal For

• Adults seeking natural mood & sleep support without synthetic alternatives
• Users preferring plant-sourced supplements with botanical origins
• Those wanting B-vitamin metabolic support alongside neurotransmitter precursors

How It Works – The Science Behind 5-HTP

5-HTP (5-Hydroxytryptophan) serves as the immediate metabolic precursor to serotonin, one of your body’s most important neurotransmitters. This direct pathway means 5-HTP can efficiently cross the blood-brain barrier and support serotonin synthesis where it’s needed most. Once serotonin is produced, it can naturally convert to melatonin in the pineal gland, supporting your body’s natural sleep-wake cycle.

The inclusion of B vitamins B3 (niacin) and B5 (pantothenic acid) provides essential metabolic and nervous system support. These B vitamins work synergistically with 5-HTP by supporting general energy metabolism and nervous system function. While B6 plays the most direct enzymatic role in converting 5-HTP to serotonin, the B3 and B5 in this formula provide foundational metabolic support for optimal neurotransmitter function.

Key Mechanisms:

• 5-HTP from Griffonia simplicifolia → increases available substrate for serotonin synthesis
• Serotonin production → contributes to mood regulation and converts to melatonin for sleep support
• B3 & B5 support → enhance energy metabolism and nervous system function

Clinical Evidence & Research Highlights

Research demonstrates that 5-HTP shows promise across multiple wellness areas, with typical effective ranges varying by intended use. Clinical studies have explored doses from 100-300 mg daily for mood support, while sleep research has examined ranges of 200-400 mg daily. The evidence base shows generally positive outcomes, though individual responses can vary significantly.

What Studies Show:

• Faster sleep onset and improved sleep quality reported across multiple clinical trials
• Mood benefits observed at therapeutic ranges, though full effects may take several weeks to develop
• Generally well-tolerated safety profile at common doses, with GI side effects being dose-related
• Promising but mixed evidence base — effect sizes vary and results depend on individual factors and dosing

The strength of evidence continues to grow, with researchers noting that 5-HTP’s effects are often condition-specific and dose-dependent, making personalized approaches important for optimal outcomes.

Product Specifications & Usage

Ingredient Breakdown

Serving size: 1 capsule (260 mg total)

• 5-HTP extracted from Griffonia simplicifolia seeds
• Vitamin B3 (Niacin) for metabolic support
• Vitamin B5 (Pantothenic Acid) for nervous system function

Package: 30 capsules per bottle

Suggested Use

Adults: Take 1 capsule daily after food to minimize potential GI effects. Do not take with milk or protein-rich drinks as these may reduce absorption and transport efficiency.

Storage: Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Check expiration date and batch number on bottle.

Dosage Guidance & Practical Usage

Educational Dosing Ranges

While individual needs vary, research suggests these general ranges for reference:

• Starting dose: 50-100 mg daily to assess individual tolerance
• Typical mood support: 100-300 mg daily, divided or single dose
• Sleep research ranges: 200-400 mg taken before bedtime

Timing & Food Considerations

Meal timing: Always take after food to reduce potential nausea or GI upset
Avoid interactions: Skip milk and protein-rich shakes around dosing time
Sleep timing: If using for sleep support, take 30-60 minutes before bedtime
Gradual introduction: Start with lower amounts, monitor effects for 3-7 days, then adjust gradually

Timeline Expectations

• Sleep effects: Some users notice improvements within days to 2 weeks
• Mood benefits: Often require 2-6 weeks for full development
• Appetite changes: Variable timeline; monitor over several weeks

Safety Information & Contraindications

Absolute Contraindications – Do Not Use If:

• Taking SSRIs, SNRIs, MAO inhibitors, or other serotonergic medications (risk of serotonin syndrome)
• Pregnant or breastfeeding women
• Children under 18 years of age
• Diagnosed bipolar disorder or schizophrenia without psychiatric supervision
• Serious chronic illness without physician approval

Important Drug Interactions

5-HTP can interact dangerously with antidepressants (SSRIs, SNRIs, TCAs), MAOIs, certain migraine medications (triptans), and dopaminergic agents. These combinations can lead to serotonin syndrome, a potentially serious medical condition.

Common Side Effects

Most users tolerate 5-HTP well, but some may experience:

• Nausea or GI upset (usually dose-related)
• Diarrhea or digestive changes
• Drowsiness or fatigue
• Vivid dreams or altered sleep patterns

Serious But Rare Risks

• Serotonin syndrome when combined with other serotonergic drugs (medical emergency)
• Allergic reactions (rare but possible)

Long-Term Use Considerations

Limited long-term safety data exists for extended 5-HTP use. Medical supervision is recommended for use exceeding 3 months, with periodic reassessment to ensure continued appropriateness.

Important Disclaimer: This product is a dietary supplement, not a medicine. If you are taking medications, have a medical condition, or are pregnant/nursing, consult your healthcare provider before use.

Why This Formulation Matters

Plant-Sourced Griffonia Simplicifolia

Our 5-HTP derives from Griffonia simplicifolia seeds, a West African plant that naturally contains high concentrations of 5-HTP. This botanical source provides traceability and represents a more natural approach compared to synthetic alternatives.

B-Vitamin Synergy

The inclusion of Vitamins B3 and B5 provides metabolic support that complements 5-HTP function. While this formula doesn’t include B6 (which plays a direct enzymatic role in 5-HTP to serotonin conversion), the B3 and B5 support overall nervous system health and energy metabolism. Users may consider dietary B6 sources or a separate B-complex supplement for enhanced enzymatic support.

Clean, Targeted Formula

This straightforward formulation avoids complex blends, making it easier to track individual responses, potential interactions, and optimal dosing for your specific needs.

Quality Assurance & Testing

Supply Chain Transparency

Our 5-HTP sources from carefully selected Griffonia simplicifolia seeds with verified regional origins. The extraction process maintains standardization to ensure consistent potency across batches.

Third-Party Testing

Every batch undergoes comprehensive testing for:

• Heavy metals (lead, mercury, cadmium, arsenic)
• Microbiology (bacteria, yeast, mold)
• Identity & potency verification
• Contaminant screening for synthesis-related impurities

Quality Certifications

• Certificate of Analysis (CoA) available by batch number
• GMP (Good Manufacturing Practice) facility production
• Non-GMO verified ingredients
• Suitable for vegetarians

Consumer Verification

To verify quality, look for:

• Batch number and expiration date on bottle
• Downloadable CoA matching your batch
• GMP certification and independent lab testing
• Clear botanical source identification (Griffonia simplicifolia)

Decision Guidance & Comparisons

5-HTP vs. Other Options

5-HTP vs. Melatonin: 5-HTP works as a precursor, supporting both serotonin and eventual melatonin production, while melatonin directly affects sleep cycles. Use cases differ based on whether you need mood support alongside sleep benefits.

5-HTP vs. Tryptophan: 5-HTP bypasses the rate-limiting step in serotonin synthesis, making it a more direct precursor than L-tryptophan.

5-HTP + B Complex vs. 5-HTP Alone: B6 specifically enhances 5-HTP to serotonin conversion. Consider B6-containing products or separate B-complex supplementation for enhanced enzymatic support.

Decision Prompts

• Primary need is sleep onset: Consider evening timing with higher doses as used in clinical sleep studies
• Mood support is main goal: Expect gradual onset over weeks; consider B6 supplementation and clinical oversight
• Currently on medications: Mandatory consultation with healthcare provider before starting

Who This Is For

Ideal Candidates

Sleep Seekers: Adults looking for natural sleep onset support through serotonin-melatonin pathways
Mood Supporters: Those seeking gentle, plant-based mood balance assistance
Stress-Sensitive Adults: Individuals wanting evening relaxation and stress resilience support

Not Suitable For

Medication Users: Anyone taking antidepressants, MAOIs, or serotonergic drugs
Pregnant/Nursing Women: Safety not established for reproductive periods
Children: Not formulated or tested for pediatric use
Psychiatric Conditions: Requires professional supervision for bipolar disorder or schizophrenia

Expected Timeline & Monitoring

What to Expect

Days 1-7: Assess tolerance; some users notice initial sleep improvements
Weeks 2-4: Sleep patterns may stabilize; early mood changes possible
Weeks 4-6: Full mood benefits typically develop; evaluate overall response
Beyond 6 weeks: Consider professional evaluation for continued use

Monitoring Guidelines

Track sleep quality, mood changes, energy levels, and any side effects. Maintain consistent timing and dosing for accurate assessment. Consult healthcare providers for persistent side effects or lack of expected benefits.

Frequently Asked Questions

Is 5-HTP safe for most adults?
Generally safe at common doses, but requires medical consultation for anyone with health conditions or taking medications.

How long until I notice effects?
Sleep improvements may appear within days to 2 weeks; mood benefits typically take 2-6 weeks to fully develop.

Can I take this with my antidepressant?
No – this creates serious risk of serotonin syndrome. Always consult your prescribing physician.

Is daily long-term use safe?
Limited long-term data exists. Professional supervision recommended for use exceeding 3 months.

Why B3 & B5 instead of B6?
B3 and B5 provide metabolic support, while B6 specifically aids 5-HTP conversion. Consider dietary B6 or separate supplementation.

Will this make me drowsy during the day?
Possible, especially when starting. Evaluate your individual response before driving or operating machinery.

Is this synthetic or plant-derived?
Our 5-HTP comes from plant-derived Griffonia simplicifolia seeds, not synthetic sources.

What about stomach upset?
Take with food and start with lower amounts. Reduce dose if GI effects persist and consult a healthcare professional.

This product is a dietary supplement and is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult your healthcare provider before starting any new supplement regimen, especially if you have medical conditions or take medications.